Caltech Nanofabrication Group

  • Increase font size
  • Default font size
  • Decrease font size
Home Research Microfluidics/Biomedical

Microfluidic Vias Enable Nested Bioarrays and Autoregulatory Devices in Newtonian Fluids

Research Area: Microfluidics/Biomedical Year: 2006
Type of Publication: Article Keywords: autoregulation, microelectromechanical devices, polydimethylsiloxane, array logic
Authors: Emil Kartalov; Chris Walker; C. R. Taylor; W. F. Anderson; Axel Scherer
Journal: Proceedings of the National Academy of Sciences Volume: 103
Number: 33 Pages: 12280-12284
Month: August
Abstract:
We report on a fundamental technological advance for multilayer polydimethylsiloxane (PDMS) microfluidics. Vertical passages (vias), connecting channels located in different layers, are fabricated monolithically, in parallel, by simple and easy means. The resulting 3D connectivity greatly expands the potential complexity of microfluidic architecture. We apply the vias to printing nested bioarrays and building autoregulatory devices. A current source is demonstrated, while a diode and a rectifier are derived; all are building blocks for analog circuitry in Newtonian fluids. We also describe microfluidic septa and their applications. Vias lay the foundation for a new generation of microfluidic devices.
Full text:
PDF: Caltech only
Online version (publisher)

Contact

Administrative and Financial Contact

Kate Finigan
MC 200-36, Caltech
1200 E California Blvd
Pasadena, CA 91125

Office:  212 Sloan Annex
Phone:  626.395.4585
Fax: 626.577.8442
Email: kate@caltech.edu

Login