Caltech Nanofabrication Group

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Microfluidics/Biomedical

Description

FluidicsOur ability to fabricate devices on the scale of biological structures and processes opens up a new world of opportunities for interdisciplinary research and biomedical technology.  We are actively developing implantable glucose and ion sensors. These integrated devices contain all necessary power, sensor, and communications systems, and with dimensions around 100um, these represent a new era of personalized medicine, where instant diagnosis and individualized drug administration become possible with continuous blood monitoring. Additionally, these characteristics are ideal for in vivo neural probes, enabling long-term monitoring of complex neural circuits at greatly enhanced resolution, critical for minimizing the risks of neuro surgery while providing a deeper understanding of brain function.  We're also leveraging our expertise in designing microfluidic systems, electronic and optical sensors to develop low-cost, integrated PCR devices in order to provide widely available disease diagnostics to developing nations, targeting areas where proper facilities and trained personel might not otherwise be accessible.

  

Members

Alumni

  

Publications

  • Scherer, A. (2015). A multiplex PCR assay for the simultaneous detection of Chlamydia trachomatis, Neisseria gonorrhoeae, and Trichomonas vaginalis”. Experimental and Molecular Pathology, 98(2), 214. [More] 
  • Rajagopal, A., Scherer, A., Homyk, A. & Kartalov, E. (2013). Supercolor Coding Methods for Large-Scale Multiplexing of Biochemical Assays. Analytical Chemistry, 85(16), 7629-7636. [More] 
  • Maltezos, G., Lee, J., Rajagopal, A., Scholten, K., Kartalov, E. & Scherer, A. (2011). Microfluidic Blood Filtration Device. Biomedical Microdevices, 13(1), 143-146. [More] 
  • Maltezos, G., Johnston, M., Taganov, K., Srichantaratsamee, C., Gorman, J., Baltimore, D. et al. (2010). Exploring the Limits of Ultrafast Polymerase Chain Reaction Using Liquid for Thermal Heat Exchange: A Proof of Principle. Applied Physics Letters, 97(26), 264101. [More] 
  • Maltezos, G., Chantratita, W., Gomez, A., Gomez, F., Kartalov, E. & Scherer, A. (2010). Portable Real-Time PCR for Rapid Viral Identification. IVD Technology, 16(7). [More] 

Contact

Administrative and Financial Contact

Kate Finigan
MC 200-79, Caltech
1200 E California Blvd
Pasadena, CA 91125

Office:  215 Powell-Booth
Phone:  626.395.4585
Fax: 626.577.8442
Email: kate@caltech.edu

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